儿童简单英语小故事_【快资讯】

来自 : 发布时间：2025-04-03

苏州蚂蚁淘生物科技有限公司成立于2017年，致力于将全球领先的创新产品和前沿技术带入中国，帮助国内科研工作者在第一时间接触世界范围内的技术革命，并分享研发工具的进步带来的技术红利。依托于集团公司深厚的资源和超过400家的国内优质客户群体，生命科学领域的一站式供应链体系，以及高风险生物危险材料进出口平台的优势，蚂蚁淘生物严格筛选国际创新且经过同行验证过的产品和技术，引入中国市场，开发、孵育和推广。公司的未来将立足于实验室大数据整合和电子商务，结合严格的品牌筛选、创新的营销模式、专注的应用支持和坚实服务，帮助实现生命科学产业链的简单和高效。

美国Pfenex公司总部在加利福尼亚的圣迭戈，是一家为生物制药和疫苗开发机构提供临床前cGMP级蛋白质的全球领先供应商。利用公司的核心技术——Pfēnex Expression Technology™在重组蛋白表达方面的应用，使Pfenex能够快速开发和生产高质量的蛋白和蛋白试剂。现Pfenex公司通过旗下的Reagent Proteins分部为全球药物研究和开发机构生产并销售相关蛋白产品。Pfēnex Expression Technology™核心专利技术结合了一个自动启用高通量平行菌株筛选技术，提供前所未有的能快速成功识别表达高可溶性滴度和活性蛋白的菌株。Pfenex公司已正式授权上海权阳贸易有限公司为中国地区首家且独家产品代理经销商。

Salmon thrombin （三文鱼凝血酶/鲑鱼凝血酶）

Catalog Number

SEA-135

Description

Plasma protein from the blood of farmed S. salar

Product Background

Background:- Fibrin gels made from salmon proteins have demonstrated remarkable properties in neuron survival and growth.- Salmon fibrin gels represent the optimal matrix for neuronal cell cultural- Salmon fibrin gels have also properties superior to mammalian gels in an in vitro angiogenesis model. The salmon gels were 60-188% more efficient than human fibrin gels supporting growth of human endothetlial cells. These results indicate that salmon fibrin may be attractive alternate ECM for support of microvascular network formation.- Salmon fibrinogen and thrombin can be used at room temperature- Soft salmon fibrin gels have been shown to promote selection and growth of tumorigenic cellsResearch Targets:- Regenerative Medicine- Spinal Cord Injury- Neural cell regrowth- Pain & CNSInvestigators- Stem Cell Research- Cancer stem cell researchBenefits:- Superior Performance- demonstrated superiority to Matrigel as an extracellular matrix for neuronal cell growth.- Safety from mammalian pathogens- Easy of rehydration & improved thermal properties.For more information on Salmon fibrinogen and thrombin:Sieminski and Gooch. 2004. J Biomater Sci Polym. Ed 15(2):237-42Ju, et al. Biomaterials. 2007 April; 28 (12): 2097-2108Liu J, et al. Nat Mater. 2012 Jul 1;11(8):734-41. doi: 10.1038/nmat3361.Information SheetApplication Note

Category

Miscellaneous Proteins

Formulation

Dialyzed in 200 mM Tris, 3 mM CaCl2, 0.15M NaCl, pH 7.2-7.5.

Reconstitution

Rehydrate with H2O at room temperature or below. Remove the amount to be used that day, and hold on ice. Salmon thrombin retains greater than 80% activity after 24 hours on ice. Aliquot remaining thrombin and freeze at <-60°C

Storage

Freezer (<-10°C). Avoid freeze-thaw cycles

Purity

Affinity chromatography on immobilized heparin, SDS-PAGESourced from salmon shown by certified tests to be negative for fish viruses. Activity tested by spectrophometric analysis of peptide hydrolysis (Chromozyme), and compared to human standard.Filtered to 0.2 u

Activity

≥ 1000 Units/ mg protein

References

US Patent #6,007,811 and 6,861,225. Michaud et al, 2002. Thrombosis Research 107:245-54Sieminski and Gooch. 2004. J Biomater Sci Polym. Ed 15(2):237-42Ju, et al. Biomaterials. 2007 April; 28 (12): 2097-2108Salmon fibrin treatment of spinal cord injury promotes functional recovery and density of serotonergic innervationLiu J, et al. Nat Mater. 2012 Jul 1;11(8):734-41. doi: 10.1038/nmat3361.

ReagentProteins is the Source for proteins.From custom protein production to our over 5,000 catalog proteins, we are a leading supplier of reagent, pre-clinical and cGMP grade proteins to the biopharmaceutical and vaccine development community. We ensure the cost-effective and rapid delivery of high quality recombinant proteins to enable your research and development efforts.

苏州蚂蚁淘生物科技有限公司再次签约美国Sea Run Holdings公司中国区独代授权商(Sole Agency Agreement)。我司已同美国Sea Run Holdings公司签约合作多年，共同合作研究开发再生医学研究试剂，力争为广大的科研工作者提供更好，更专业的服务。Salmon fibrinogen (SEA-133) and fibrin ECM鲑鱼蛋白原Excellent proliferation of stem cells and retention of \"stemness” (Zhou et al. Stem Cell Trans. Medicine. 2017;6(5):1412-1423)Superior to Matrigel for neurite outgrowth and neuronal cell growth (Ju et al. Biomaterials. 2007 April; 28 (12): 2097-2108)More efficient ECM (60-188%) than human derived fibrin gels for angiogenesis. (Sieminski et al. 2004. J Biomater Sci Polym. Ed 15(2):237-42)Slower gel degradation in vitro and in vivoSelection and growth of tumorigenic cells (Liu J et al. Nat. Mater. 2012 Jul 1, 11(8):734-41)Salmon thrombin (SEA-135)鲑鱼凝血酶Optimal polymerization of salmon fibrinogenSignificant and sustained analgesia for pain studies (Weisshaar et al. 2011 Biomaterials:9738-9746)Potential alternative for opioids.Blocks disruption of blood-brain barrier. (Smith et al. 2016. BioMaterials 80: 96-105).

Pfenex表达技术（Pfenex Expression Technology）平台最初是在陶氏化学公司内部开发的，经过几年平台的研究和开发，Pfenex Inc.于2009年12月从陶氏剥离出来。Pfenex Inc.从2009年开始作为一家私营生物技术公司存在，直到2015年IPO上市。

当Pfenex脱离陶氏时，公司获得了与Pfenex Expression Technology平台相关的整个知识产权，位于加利福尼亚州圣地亚哥的陶氏研发中心以及支持该业务的整个团队都留在了该公司，直到今日，公司仍然有许多创始团队的成员留在Pfenex。

Pfenex公司的主要候选产品包括：

• PF708，一种用于治疗骨质疏松症的Forteo（teriparatide）的治疗等效候选药物

• 新型炭疽疫苗候选物，如Px563L和RPA563，目前处于 I 期研究阶段

• PF529，Neulasta的生物仿制药候选药物

• PF530，Betaseron的生物仿制药候选药物

• 血液学/肿瘤学产品，包括PF743和PF745

Pfenex Inc.与Jazz Pharmaceuticals Ireland Limited、Hospira, Inc.以及The National Institute of Allergy and Infectious Diseases签署有合作协议。

热心细致的服务态度打造温暖亲切的购物氛围，有任何问题欢迎随时联系我们！苏州蚂蚁淘生物科技有限公司SuZhouebiomallBIOLOGicalTechnologyCo.,Ltd.总部地址:苏州园区星湖街218号苏州生物医药产业园一期（生物纳米园）A4-216服务热线:4000-520-616（限工作日9:00-18:00）固话：0512-67156496手机：18915418616QQ：3507623898、3464842061、1570468124传真:0512-67226173Email:info@ebiomall.com